Yes, that is possible. You're going to want to share a packaged workbook or at the very least, screenshots of your view layout so that you can get maximum help from the community.
In general, you'll likely end up creating a calculated field that partitions your view into the appropriate splits.
If you need to make it so a "single record" in your source data needs to contribute to two distinct columns (LastYearTotal and LYQ1, LYQ2, LYQ3 and LYQ4), you will likely have to create a calculated field for each column and utilize the Measure Values and Measure Names control pills.
Can you share the calculation syntax for the two measures you're showing?
Also, you probably do not need to use 2 different parameters for ACT and PRY (assuming they are Actual date and Prior Year).