Sure - you could just utilize a field in place of the existing thumbnails link.
I did this quickly by creating a new field on the ThumbnailLink view- we just want to search for an instance where more than one item in that filter has been selected so window_max(Index()) > 1 is the condition.
if window_max(index())>1 then "http://mycmag.kantarmediana.com/404" else attr([Thumbnail Link]) END
Setting the field to Compute Using [ThumbtailLink] or else it won't work right to calculate the max value of index.
Then we can set the value to return to the view to whatever we want.. i return a 404 in the url sample but it could be a custom image saying "no image" that is on the web server.