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I'm not sure I completely understand this layout. However, from what is written, I believe you want to make a selection in the first filter, and based on that select different values will appear in the other filters? Then, selecting one of those will give you the data?
If this is the kind of functionality you are referring to, then yes, by using Only Relevant Values in the subsequent quick filters will only show data that is available based on the previous quick filter. To use this function, right click in the upper right corner of the quick filter and select Only Relevant Values.
Hope this helps!