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My work machine is a Windows 10 laptop, my personal machine is a MacBook Pro running OS X 10.something (NOT the latest, probably about 2 dot versions behind).
That's been my setup for many years, I use Tableau on both in exactly the same way - twb & twbx files are completely interchangable. The ONLY thing that I miss on OS X (and only sometimes) is when I need to create a legacy connection to an Excel file in order to write Custom SQL ... you can't do that on OS X. That said, the last time I needed to do something like that was approx a year ago.