So you would like to exclude Orange value
from summing up Total of Header2 Measure?
It could be done by using a custom total calc like this:
// Header2 Modified Calc
IF MIN([Fruits]) = MAX([Fruits]) // this condition defines a Total cell
if [Fruits] != 'Orange' then [Header2] END // this is a filter inside of an aggregate
ELSE SUM([Header2]) // this is for the rest of your table
Hope it could help