This comes around (often!), the answer is why would you want to? and then followed by no/ yes...
See this thread as an example: How to display more than 16 columns/rows in tableau?
Idea: (with comments) http://community.tableau.com/ideas/2628
No still we can use 16 columns.
We will go with mark advice or else wait for new version.
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I don't think it is likely that a new version will address this either -- Tableau features are centered around best practices, and increasing that limit would be outside of what I'd expect Tableau to do to address your issue.
You can also hack the XML to increase the limit, I believe, but this is unsupported.